Pharmacology

Vivotecnia offers a wide range of animal models for studying the efficacy of drugs. Our working process allows us to rapidly respond to the needs of our clients.

We can adapt our standard studies to your requirements as well as set up new protocols in order to meet your needs, from drug discovery to pre-clinical development.

Vivotecnia’s personnel can offer advice to our clients regarding the most appropriate assays for product evaluation, as well as provide analysis of the results.

 

The following experimental models are among our areas of expertise:

Pharmacodynamic models

Safety pharmacology

Behaviour

Morris Water Maze assay
Object Recognition assay

Metabolism
Hyperglycaemia model
Hyperlipaemia model

Blood clotting

Platelet aggregation model
Prothrombin time test

Inflammation

Dorsal granuloma assay
Paw oedema assay
Ear oedema assay

Carcinogenesis models
Xenograft

In vitro cytotoxicity
Dermal carcinogenesis

Central Nervous System (CNS)
Irwin test / Motor coordination
Peripheral analgesia model
Anticonvulsant activity test
Sedative activity test

Gastrointestinal system
Evaluation of gastric secretion
Evaluation of intestinal motility
Models of induced gastric ulcers

Renal system
Determination of renal and urinary parameters

Immune system
Passive Cutaneous Anaphylaxis (PCA)
Proliferation assays
Efficacy of vaccines and adjuvants
Endocrine function