The in vivo nude mouse xenograft model is a useful tool to investigate the events involved in cell malignant transformation, invasion and metastasis, as well as to evaluate the efficacy and/or mechanisms underlying therapeutic approaches. Vivotecnia hold a range of cell lines from breast, colorectal, brain, connective tissue, lung, skin, bone, pancreas and muscle available for establishment (cell dose/animal, vehicle, volume of administration etc to define the tumour volume growth post-cell inoculation).
Additional efficacy models available include:
- Inflammation (collagen induced arthritis model)
- Diabetes (streptozotocin-induced diabetes model)
- Sepsis (Lipopolysaccharide-induced sepsis model)
We are experienced in developing new efficacy models. We will be pleased to evaluate how we can help you in your research project.
We are experienced in developing new efficacy models
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