Inhalation Methodology

Inhalation Toxicity for the Testing of Chemicals :

  • Acute Inhalation Toxicity – Acute Toxic Class Method in Rat. OECD 436
  • Acute Inhalation Toxicity. OECD 403; OPPTS 870.1300
  • Subacute Inhalation Toxicity: 28-Day Study. OECD 412
  • Subchronic Inhalation Toxicity: 90-Day Study. OECD 413; OPPTS 870.3465
  • Guidance document on acute inhalation toxicity testing. Number 39. ENV/JM/MONO(2009)28

Inhalation Toxicity for the Testing of Tobacco :

  • Tobacco and tobacco products-Atmosphere for conditioning and testing. ISO 3402
  • Cigarettes-Determination of total and nicotine-free dry particulate matter using a routine analytical smoking machine. ISO 4387
  • Routine analytical cigarette-smoking machine-Definitions and standard conditions. ISO 3308
  • Standard Operating Procedure for Intense Smoking of Cigarettes (World Health Organization)
  • ISO and Health Canada intense smoking parameters. ISO/TR 19478 Part 1(2014) and Part 2 (2015)

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