Vivotencia offers our clients a wide range of tests for safety assessment of cosmetic and cosmetic ingredients. Our team of experts and partners has validated “in-house” the in vitro methods approved by the European Centre for the Validation of Alternative Methods (ECVAM) for cytotoxicity and local toxicity (cutaneous and ocular irritation) assessment, as well as phototoxicity evaluation for photoreactive compounds.

All the assays are conducted in strict adherence to GLP principles and the requirements of the European Cosmetics Regulation EC 1223/2009.

Currently Vivotecnia offers the following studies:

Cytotoxicity test

  • Neutral Red Uptake (NRU, NRR)
  • MTT Assay

Local cutaneous and ocular toxicity

  • Epidermal Skin Test (OECD 431)
  • In vitro Skin Irritation (OECD 439)
  • EpiOcularTM  (OECD 492)

Phototoxicity test

  • In vitro 3T3 NRU phototoxicity test. (OECD. 432)

Mutagenicity test

  • Ames Test
  • Comet Test



Please contact us to discuss your particular needs and goals.

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