Our in-house team of veterinarians ensure that animal welfare is paramount and are committed to the principals of the 3Rs (refinement, reduction, replacement). Our ethical review process ensures that studies are performed with a sound scientific background, using an appropriate number of animals, and operating in strict accordance with EU regulations.
Utilising the expert advice of individuals from within the CRO industry with long experience with non-human primates, we designed our state of the art non-human primate unit. Extensive training of our study directors and animal technicians followed.
We can therefore provide an alternative second non-rodent species where dog is not deemed an appropriate species (receptor binding information, metabolism differences or lack of systemic exposure relative to expected human therapeutic exposure, etc).
State of the art gang housing exceeding the standard welfare regulations:
- Adjacent caging mechanism allowing capture / observation of animals
- Environmental enrichment including foraging, toys, swimming pool, TV, swings
- Positive reinforcement used (dosing and procedures)
- Unit for PK Studies (capacity 20 animals)
- Unit for toxicology studies (capacity 40 animals)
- European Union Directive 2010-63- EU on the protection of animals used for scientific purposes
(translated into Spanish national law RD 53/2013)
- ICH Harmonized Tripartite Guideline M3 (R2): “GUIDANCE ON NONCLINICAL SAFETY STUDIES
FOR THE CONDUCT OF HUMAN CLINICAL TRIALS AND MARKETING AUTHORIZATION FOR
- ICH Harmonized Tripartite Guideline S6 (R1): “PRECLINICAL SAFETY EVALUATION OF
Our team and Experience
For Vivotecnia it is essential that those involved with the care and use of non-human primates for scientific purposes ensure that their use is ethical and humane, and complies with all relevant legislation and guidelines. Vivotecnia is fully committed to training and retention of skilled staff in NHP research in order to ensure the highest standards of animal welfare and study performance.
Before conducting any project, the use of NHP for each study is approved by Vivotecia´s Animal Ethics Committee, which members are highly trained and skilled to collaborate with you in improving study design in order to fulfill animal welfare requirements.
Our Study Directors, Technical staff, and In-house Veterinarians accumulate years of practical experiences and skills in NHP medicine, NHP caregiving, monitoring, and procedures. Vivotecnia integrates these skills with state of the art facilities to provide a solid base for ensuring NHP cooperation with procedures, reducing animal stress and improving animal welfare, not only for ethical reasons but also with the aim of providing you with reliable and predictive models for safety and efficacy testing.
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