pharmacokinetics

Pharmacokinetics

Animal models: rodent (mice, rat, hamster, guinea pig) and non-rodent (rabbit, dog, minipig, NHP).

Dosing routes:

  • Oral: gavage, capsules, pills
  • Intravenous
  • Subcutaneous
  • Dermal
  • Intra-dermal
  • Intramuscular
  • Intraperitoneal
  • Intra-nasal
  • Intra-vaginal
  • Intra-rectal
  • Ocular
  • Advanced bioanalytical method development
  • Method transfer
  • Method qualification pharmacokinetics (PK) services
en blanco
Our team and experience
Vivotecnia can provide advice and respond to your needs with a comprehensive range of preclinical pharmacokinetic and metabolism studies. These can be offered either as a stand-alone service or as part of an integrated offer.

Our expert team and strategic partners are well versed in GLP regulations and by using only the state-of-the-art instrumentation and the most up-to-date methods, together we can perform studies with significant cost savings to clients. Our pharmacokinetic and metabolism scientists can provide the following services, to characterize the absorption, distribution, metabolism, and excretion (ADME) profiles of your compound:

  • In vivo Pharmacokinetics/toxicokinetics
  • Bioanalytical methods development and validation
Methodology

Pharmacokinetic/toxicokinetic studies

  • Note for guidance on toxicokinetics: the assessment of systemic exposure in toxicity studies, ICH S3A, October 1994
  • Pharmacokinetics: guidance for repeated dose tissue distribution studies, ICH S3B, October 1994
  • Guideline on the evaluation of control samples for non-clinical safety studies: checking for contamination with the test substance, EMA/CPMP/SWP/1094/04, March 2005

CONTACT

For more information or a formal quotation, please send us a message and we will contact you as soon as possible.



You may also be interested in…

safety pharmacology services

Safety Pharmacology

Safety pharmacology satisfies a key requirement in the drug development process, assessing any potential adverse effects that drug candidates may have on the body’s major physiological systems

inhalation services

Inhalation

Inhalation toxicity studies are required to assess the exposure hazards of consumer products or to manufacturing workers

General Toxicology

Our team of experienced, highly-educated scientists, experts in toxicology, molecular biology, chemistry and immunology fully understands that the drug development process is distinct for each approach

config