Animal models: rodent (mice, rat, hamster, guinea pig) and non-rodent (rabbit, dog, minipig, NHP).

Dosing routes:

  • Oral: gavage, capsules, pills
  • Intravenous
  • Subcutaneous
  • Dermal
  • Intra-dermal
  • Intramuscular
  • Intraperitoneal
  • Intra-nasal
  • Intra-vaginal
  • Intra-rectal
  • Ocular
  • Advanced bioanalytical method development
  • Method transfer
  • Method qualification pharmacokinetics (PK) services
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Our team and experience

Vivotecnia can provide advice and respond to your needs with a comprehensive range of preclinical pharmacokinetic and metabolism studies. These can be offered either as a stand-alone service or as part of an integrated offer.

Our expert team and strategic partners are well versed in GLP regulations and by using only the state-of-the-art instrumentation and the most up-to-date methods, together we can perform studies with significant cost savings to clients. Our pharmacokinetic and metabolism scientists can provide the following services, to characterize the liberation,  absorption, distribution, metabolism, and excretion (LADME) profiles of your compound:

  • In vivo Pharmacokinetics/toxicokinetics
  • Bioanalytical methods development and validation

Pharmacokinetic/toxicokinetic studies

  • Note for guidance on toxicokinetics: the assessment of systemic exposure in toxicity studies, ICH S3A, October 1994
  • Pharmacokinetics: guidance for repeated dose tissue distribution studies, ICH S3B, October 1994
  • Guideline on the evaluation of control samples for non-clinical safety studies: checking for contamination with the test substance, EMA/CPMP/SWP/1094/04, March 2005


    For more information or a formal quotation, please send us a message and we will contact you as soon as possible.

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