Inhalation toxicity studies are required to assess the exposure hazards of consumer products or to manufacturing workers.

In accordance with OECD chemical testing guideline requirements, inhalation studies are designed “to satisfy hazard classification and labeling requirements, to estimate the toxicity of mixtures, and to assess human health and environmental risk”.

Acute inhalation toxicity studies can also characterize hazards associated with consumer products (e.g. biocides for indoor use, multipurpose spray cans, aerosolized cleaning agents, incense to repel insects).

Repeated-exposure inhalation toxicity data are used to satisfy hazard characterization requirements with an emphasis on the NOAEL. As such, these studies focus primarily on characterizing toxic mechanisms and exposure atmospheres causing health hazards to repeatedly exposed humans rather than on classifying and labeling substances or mixtures as marketed.

Our services ensure compliance with OECD guidelines for acute inhalation studies and for repeated administration through inhalation.

Furthermore, as inhalation administration is an active area for pharmaceutical drug development, inhalation toxicity studies are aimed at potential inhaled therapeutic products.

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Tobacco inhalation studies:

Tobacco inhalation studies are designed to assess the toxicological effects of mainstream smoke (standard cigarettes) or smoke aerosol (e-cigarettes and heat-not-burn cigarettes).



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