Nonclinical Toxicology

Pharmacokinetic Studies

We perform pharmacokinetic (PK) studies to assess the absorption, distribution, metabolism and excretion (ADME) profile of their compounds. These in vivo studies provide crucial data for understanding systemic exposure and supporting dose selection in regulatory toxicology programs.

Preclinical regulatory CRO

Established – 2000

Strategic data for early-stage decisions

Our PK studies are designed to help predict a compound’s behavior in the body, detect potential issues early, and inform decisions about dosing and safety margins. These studies are typically carried out in rodent and non-rodent species using various administration routes and biological matrices.

Determination of plasma concentration-time profiles, calculation of key PK parameters and others
Cmax, Tmax, AUC, T1/2
Matrices: CNS, Milk
Administration routes: oral, intravenus, subcutaneous, dermal, and inhalation
Different animal models: rodents and non rodents
Full bioanalytical support through our dedicated bioanalysis unit
Advantage of having PK and bioanalysis units in close proximity, ensuring seamless communication and efficient project coordination

What we offer at Vivotecnia

GLP-certified studies since 2003

OECD and ICH compliant

Predictable timelines and rapid turnaround

QA-audited, submission-ready reports

Industries we support

Pharmaceutical

Chemical

Biotechnological

Advanced Therapy Medical Products (ATMPs)

Infrastructure and equipment

Vivotecnia has a highly specialized bioanalytical unit that combines state-of-the-art technology with a multidisciplinary team of experts in regulated preclinical studies.

WHY VIVOTECNIA

Equipamiento de alto rendimiento

SCIEX Triple Quad™ LC-MS/MS, UPLC, HPLC, NanoLC 400 and robotic automation systems for sample handling.

Comprehensive digital management

Provantis® platform for document control, traceability and regulatory compliance.

Expert team

Professionals with experience in more than 4,000 preclinical studies, including mutagenicity, toxicity and pharmacokinetics.

Quality assurance

All assays are performed under GLP certification and are audited by our internal Quality Assurance unit.

Need fast and reliable PK data to support your development? Contact our pharmacokinetics team to design a customized study that fits your compound’s needs

Pharmacokinetic Studies

Strategic data for early-stage decisions