Nonclinical Toxicology
Choosing the appropriate route of administration is a critical step in the design of any nonclinical toxicology study. The selection depends on regulatory guidelines, the physicochemical properties of the compound, its intended use, and the most likely route of human exposure. At Vivotecnia, we perform studies using both conventional and non-conventional administration routes, ensuring that exposure accurately reflects clinical or real-world conditions.
Preclinical regulatory CRO
Established – 2000
We have the expertise and infrastructure to carry out administration procedures in rodents and non-rodents, always under GLP standards. Our experience guarantees consistency, safety, and reproducibility, while maintaining the highest standards of scientific rigor and animal welfare.
We guide clients in using 6-month sata within ICH S1B frameworks for possible waiver of the 2-year study when justifiedAll procedures are performed under GLP conditions and in line with EMA, FDA, OECD and ICH guidelines.
Our teams is trained in rodent and non-rodent administration, including large-volume dosing, repeated administration, and dose escalation protocols.
Each administration route follows validated protocols for volume, frequency, needle size and animal restraint, ensuring safety and data integrity.
Minimally invasive techniques, analgesia protocols and 3Rs implementation are central to all our administration procedures.
If you are looking for a committed team,
with experience and scientific vision,
Vivotecnia is your ally in preclinical
toxicology.
