General Toxicology Testing
At Vivotecnia, we offer a full suite of reproductive and developmental toxicity studies to assess the potential impact of chemical substances or pharmaceutical compounds on fertility, embryo-fetal development and postnatal outcomes. These studies are crucial to ensure that new products are safe for reproduction health and to meet international regulatory requirements.
Preclinical regulatory CRO
Established – 2000
In line with ICH guidelines (such as ICH S5), our reproductive and developmental studies cover the three classical segments of Developmental and Reproductive Toxicology (DART):
These studies can be conducted by both oral and inhalation routes, depending on the intended use of the pharmaceutical product.
For crop protection products, industrial chemicals, and other regulated substances, our studies follow OECD test guidelines, including:
As with pharmaceutical testing, these studies are performed by both oral and inhalation routes to reflect realistic exposure scenarios.
At Vivotecnia, we have extensive expertise in performing all required reproductive toxicity endpoints with precision and scientific rigor:
Necropsy and C-sections, uterine examinations, monitoring during gestation and lactation
External morphology, visceral analysis, skeletal assessments
Motor activity, learning and memory, acoustic startle response
Concentration, count, motility, morphology
Chemical
Food
Vivotecnia has a highly specialized bioanalytical unit that combines state-of-the-art technology with a multidisciplinary team of experts in regulated preclinical studies.
Specialized in complex reproductive protocols with full control of mating, parturition and neonatal care.
Even for non-GLP studies, our infrastructure ensures full environmental control and traceability.
Strict adherence to 3Rs principles and tailored environmental enrichment for each species.
In-house pathology, clinical pathology, bioanalysis and study sirection for seamless execution.
Need reproductive toxicology studies for
your regulatory submission?
Contact our experts to design a high-
quality study tailored to your compound
and development phase!
