Acute toxicity studies evaluate adverse effects occurring after oral, dermal or inhalation administration of a substance in a single dose or in multiple doses in periods of less than 24 hours.
Thanks to Vivotecnia’s ample experience, we are in a position to offer acute toxicity studies employing a comprehensive selection of administration routes, test methods, and species, providing our customers accurate data to make informed decisions regarding accidental human exposure.
All studies are performed according to global regulatory guidelines, namely OECD, FDA, EMA, EU, etc.
Acute toxicity studies:
- Dermal irritation/corrosion
- Skin irritation/corrosion
- Eye irritation/corrosion
Acute toxicity methodology
- Test No. 420: Acute Oral Toxicity – Fixed Dose Procedure
- Test No. 423: Acute Oral toxicity – Acute Toxic Class Method
- Test No. 425: Acute Oral Toxicity: Up-and-Down Procedure
- Test No. 402: Acute Dermal Toxicity
- Test No. 404: Acute Dermal Irritation/Corrosion
- Test No. 405: Acute Eye Irritation/Corrosion
- Test No. 403: Acute Inhalation Toxicity
- Test No. 436: Acute Inhalation Toxicity – Acute Toxic Class Method
Acute toxicity in vitro